Muscle Disease, Vitamin D deficiency

A similar mechanism underlies the wasting and weakness associated with lack of vitamin D (osteomalacia) in which marked atrophy of type 2 fibres may be seen. The actions of vitamin D in muscle are not fully understood, but it appears that at least one of its metabolites, 25-hydroxycholecalciferol, may influence the resting energy state of the muscle and also protein turnover.